RT - Journal Ty - Jour YR - 2009-01-31 JF - 当前世界环境Jo - Sp - Op - Vo - 10是 - 11 UL - www.a-i-l-s-a.com/article/157/ do - 10.12944 / cwe.4.1。07 N2 - 血液学和生化指数用于监测白化大鼠汽油的毒性。大鼠分别置于四组,分别腹膜内施用0.0,2.0,4.0和10.0g / kg汽油,2相2期1和2个月。在每个时期结束时,将大鼠从每组中取出进行分析。用生理盐水类似地处理对照大鼠。采取血液样品用于分析血红蛋白(HB),包装细胞体积(PCV)和白细胞计数(WBC)。血清酶如天冬氨酸转氨酶(AST),丙氨酸转氨酶(ALT),碱性磷酸酶(ALP)。同等监测谷胱甘肽-S-转移酶(GST)和谷胱甘肽(GSH)。Hb和PCV的显着降低,特别是在第四组大鼠中收到的。10gkg-1gasoline与对照和其他相比(P <0.05)。 A significant decrease in the number of white blood cells in the first month exposure to gasoline was recorded, especially in rats administered 10gkg-1gasoline. Substantial increase in the activities of liver enzymes - ALT, AST and ALP were observed in all the groups. However, GST increased marginally from first to second month in all the groups. Furthermore, there was consistent reduction in the level of GSH after the first dose in all the groups compared with control (P < 0.05). The study demonstrates that long term exposure of rats to gasoline could induce anaemia and liver damage. ER -