@article{CWE/157/2017, author={}， journal ={Current World Environment}， publisher ={}， title={汽油诱导的血液学变化和相关的肝毒性在白化大鼠中}，year ={}， month ={}， volume ={10}， url ={www.a-i-l-s-a.com/article/157/}， pages ={49-54}，采用血液学和生化指标监测汽油对白化大鼠的毒性。将大鼠分为四组，分别腹腔注射0.0、2.0、4.0和10.0g/kg汽油，为期1和2个月。在每个周期结束时，各组大鼠均被取出进行分析。对照组大鼠同样用生理盐水处理。采集血液样本，分析血红蛋白(Hb)、包装细胞体积(PCV)和白细胞计数(WBC)。血清酶如天门冬氨酸转氨酶(AST)，丙氨酸转氨酶(ALT)，碱性磷酸酶(ALP)。谷胱甘肽s -转移酶(GST)和谷胱甘肽(GSH)监测结果相同。Hb和PCV明显降低，尤其是4组大鼠。10gkg-1汽油与对照及其他汽油比较(P < 0.05)。 A significant decrease in the number of white blood cells in the first month exposure to gasoline was recorded, especially in rats administered 10gkg-1gasoline. Substantial increase in the activities of liver enzymes - ALT, AST and ALP were observed in all the groups. However, GST increased marginally from first to second month in all the groups. Furthermore, there was consistent reduction in the level of GSH after the first dose in all the groups compared with control (P < 0.05). The study demonstrates that long term exposure of rats to gasoline could induce anaemia and liver damage. }, number = {11}, doi = {10.12944/CWE.4.1.07} }